INOTUZUMAB OZOGAMICIN
About INOTUZUMAB OZOGAMICIN
INOTUZUMAB OZOGAMICIN is an anti-cancer medicine used in the treatment of acute lymphoblastic leukemia, a blood cancer that primarily affects the blood and bone marrow. INOTUZUMAB OZOGAMICIN is used in the treatment of patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
INOTUZUMAB OZOGAMICIN contains Inotuzumab Ozogamicin, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.
INOTUZUMAB OZOGAMICIN may cause certain side effects, such as skin rash, fatigue, headache, decreased platelet count, nausea, vomiting, diarrhea, abdominal pain, dizziness, myalgia, and injection site reactions. These side effects do not require medical attention and gradually resolve over time. INOTUZUMAB OZOGAMICIN is a parenteral preparation. It will be administered by a trained oncologist. Do not self-administer.
INOTUZUMAB OZOGAMICIN should be avoided if you are allergic to it or any other components present in it. Before taking INOTUZUMAB OZOGAMICIN, caution should be exercised if you have/had liver/kidney disease, gastrointestinal disorders, or cardiac problems, as it may cause serious side effects or worsen such conditions. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding before starting the treatment.
Uses of INOTUZUMAB OZOGAMICIN
Medicinal Benefits
INOTUZUMAB OZOGAMICIN contains Dasatinib, which is used in the treatment of acute lymphoblastic leukemia (ALL). It works by binding the ADC (antibody-drug conjugate) and CD22 tumor cells containing N-acetyl-gamma-calicheamicin (cytotoxic agent) and forms the ADC-CD22 complex. This complex causes the activation of N-acetyl-gamma-calicheamicin and induces DNA breakage. Thus, it helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.
Directions for Use
Storage
Side Effects of INOTUZUMAB OZOGAMICIN
- Nausea
- Diarrhoea
- Decreased platelet count
- Fatigue
- Vomiting
- Headache
- Abdominal pain
- Dizziness
- Skin rash
- Myalgia
- Pain at the site of injection
- Injection site reactions
Patients Concern
Disease/Condition Glossary
Acute Lymphoblastic Leukemia (ALL): Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. There are different types of blood cancers. ALL is a type of blood cancer that primarily affects your blood and bone marrow. It mainly targets the white blood cells, which can interfere with your body’s ability to combat infections. Symptoms may include fever, weight loss, abnormal blood cell count, bruising, and loss of appetite.
FAQs
INOTUZUMAB OZOGAMICIN contains Inotuzumab Ozogamicin, which works by inhibiting the DNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells.
INOTUZUMAB OZOGAMICIN is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman must have a negative pregnancy test before starting treatment with this medicine. Using effective birth control methods to prevent pregnancy while taking this medicine is better.
